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New paper by Francesco Iorio on Molecular Systems Biology

Tue, Jul 7 2020|

A new study by Francesco Iorio - Group Leader, Research Centre for Computational Biology - published in Molecular Systems Biology has created the most comprehensive analysis for understanding how cancer drugs work at a molecular level by combining drug response data with CRISPR genetic screens across hundreds of cancer cell lines.

The research identified the mechanism-of-action in 50 per cent of the 397 drugs tested. This improved understanding of the biological mechanisms underpinning drug response will facilitate faster, more efficient development of new cancer drugs and brings us closer to precision medicine for cancer patients.

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