Human Technopole in sintesi
Human Technopole is Italy's new research institute for Life Sciences, based at the heart of MIND - Milan Innovation District. MIND will include the new Galeazzi Hospital centre, the science campus of the University of Milan and Fondazione Triulza, a lab-hub for social innovation and sustainable development.
Human Technopole will promote human health and well-being through an interdisciplinary approach to health and aging.
The interdisciplinary approach
Human Technopole will develop personalised approaches, both in the medical and the nutritional field, aimed to fight cancer and neuro-degenerative diseases by integrating large scale genomics with the analysis of complex data systems and the development of new diagnostics techniques.
The institution will have an interdisciplinary approach based on the creation and sharing of knowledge to promote innovation in healthcare. An approach that will combine different topics: from genomics to translational and basic research, from big data analysis to the introduction of new analytical methods, from nutrition to the search of new sustainable technologies in agriculture, from the development of medical devices and innovative diagnostic tests to the processing of socio-economic data for providing new analytical solutions for the public policies decision makers.
Human Technopole will consists of seven research centres and various scientific facilities structures, that will provide services and technologies to support the research. Each centre will include its own laboratories and will collaborate with universities, research centres and hospitals.
The first areas of research currently being developed are:
Centre for Genomics
The Centre for Genomics will pursue research aimed at uncovering the complex mechanisms governing gene expression and how heritable genetic information translates into phenotypic traits.
Centre for Computational Biology
The Centre for Computational Biology will analyse and interpret the massive amounts of data generated by all other centres, build predictive models, and help to further our understanding of biological processes and their impact on human health and response to therapies. It will integrate with research pursued by the Centre for Genomics, taking computational and bioinformatics approaches to study disease-associated biological processes. It will also be active in developing new methods of image analysis that have relevance in many areas of biomedicine.
Centre for Neuro-genomics
The Centre for Neuro-genomics will investigate the mechanisms of human neuropsychiatric and neurological diseases, ranging from neurodevelopmental to neurodegenerative disorders, combining basic and translational research through different experimental systems and computational approaches (from brain organoids to animal models to epidemiological cohorts) to probe the structure, function and development of the nervous system at multiple scales of resolution.
Centre for Structural Biology
The Centre for Structural Biology will aim at gaining precise knowledge of the structure of macromolecules and their organisation within cells, which is essential to understand how they function. This area of work will be paramount to understand the molecular mechanisms by which different diseases originate in the human body and will help to develop novel drugs.
In addition to the above, the Centre for Analysis, Decisions and Society (CADS) is already operating within Human Technopole, as a joint project with Politecnico di Milano. Its main research activity lies within the field of data science. The aim of CADS is to develop advanced tools for data management and analysis and to analyse information generated by various sources (e.g. genomics data, data from the healthcare system) in order to provide decision support to policy makers, healthcare providers and other stakeholders. The Centre has been operational since 2018 and is currently in the process of selecting a director.